Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | PMM2 | O15305 | 1/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | IDE | P14735 | 1/20 | 0.52 |
| ▸ | MPI | P34949 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466906 | 0.82 | ALDH1A1 (0.72) | MEN1KMT2AGAAKDM4EPOLB | |
| SCHEMBL6417385 | 0.81 | MEN1 (0.72) | MEN1KMT2AGAAKDM4EPOLB | |
| SCHEMBL1956403 | 0.81 | MEN1 (0.66) | MEN1KMT2AGAAKDM4EPOLB | |
| SCHEMBL4063073 | 0.78 | HDAC2 (0.62) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL23200342 | 0.77 | MEN1 (0.66) | MEN1KMT2AGAAKDM4EPOLB | |
| SCHEMBL9267405 | 0.77 | MEN1 (0.62) | MEN1KMT2AGAAKDM4EPOLB | |
| SCHEMBL15652958 | 0.77 | KMT2A (0.60) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL13856753 | 0.76 | MEN1 (1.00) | MEN1KMT2AGAAKDM4EPOLB | |
| SCHEMBL7348029 | 0.76 | MEN1 (0.70) | MEN1KMT2AGAAKDM4EPOLB | |
| SCHEMBL11862064 | 0.75 | MEN1 (0.72) | MEN1KMT2AGAAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097600-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | THE WISTAR INSTITUTE (US) | 2011-08-11 | — | — | WO | disclosed |