Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | METAP2 | P50579 | 1/20 | 0.70 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.60 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.60 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.60 |
| ▸ | ACLY | P53396 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402809 | 0.88 | ACLY (0.73) | MEN1KMT2AMETAP2MCL1ALDH1A1 | |
| SCHEMBL9864681 | 0.87 | METAP2 (0.58) | MEN1KMT2AMETAP2MCL1ALDH1A1 | |
| SCHEMBL3554601 | 0.86 | MEN1 (0.57) | MEN1KMT2AMETAP2MCL1ALDH1A1 | |
| SCHEMBL9402850 | 0.85 | MCL1 (0.67) | MEN1KMT2AMETAP2MCL1ALDH1A1 | |
| SCHEMBL1466906 | 0.85 | ALDH1A1 (0.72) | MEN1KMT2AMETAP2MCL1ALDH1A1 | |
| SCHEMBL3563792 | 0.84 | MEN1 (0.55) | MEN1KMT2AMETAP2MCL1ALDH1A1 | |
| SCHEMBL1688339 | 0.84 | METAP2 (0.71) | MEN1KMT2AMETAP2MCL1ALDH1A1 | |
| SCHEMBL3564034 | 0.83 | SLC16A3 (0.55) | MEN1KMT2AMETAP2MCL1ALDH1A1 | |
| SCHEMBL1956403 | 0.83 | MEN1 (0.66) | MEN1KMT2AMETAP2ALDH1A1HSD17B10 | |
| SCHEMBL2009251 | 0.82 | METAP2 (1.00) | METAP2MCL1ALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030709-A1 | NOVEL SULFONE AMIDE DERIVATIVES CAPABLE OF INHIBITING BACE | LG LIFE SCIENCES LTD. (KR) | 2005-04-07 | — | — | WO | disclosed |