Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.39 |
| ▸ | TUBB | P07437 | 4/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1962577 | 0.80 | MAPK13 (0.39) | RXFP1KDM4EALDH1A1CLPPLMNA | |
| SCHEMBL1961887 | 0.79 | CLPP (0.39) | NPC1KMT2AKDM4EALDH1A1CLPP | |
| SCHEMBL1959835 | 0.78 | CLPP (0.38) | NPC1RAB9ATUBB4ATUBBTUBA3C | |
| SCHEMBL1959748 | 0.76 | CLPP (0.37) | KDM4EALDH1A1CLPPHSP90AA1LMNA | |
| SCHEMBL1962303 | 0.76 | RAB9A (0.44) | NPC1RAB9AKMT2ARXFP1KDM4E | |
| SCHEMBL2345294 | 0.76 | CXCR2 (0.39) | KDM4EALDH1A1CLPPHPGDMAPK1 | |
| SCHEMBL1962289 | 0.75 | NPC1 (0.38) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL1961441 | 0.75 | PTGES (0.40) | NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1960359 | 0.75 | NPC1 (0.35) | NPC1KDM4EALDH1A1CLPPHPGD | |
| SCHEMBL1958963 | 0.74 | OPRK1 (0.37) | NPC1RAB9AKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332938-B1 | Viral inhibitors | LEUVEN K U RES & DEV (BE) | 2014-10-01 | — | — | EP | disclosed |
| US-8779141-B2 | Viral inhibitors | GILEAD SCIENCES, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| EP-1521754-B1 | VIRAL INHIBITORS | LEUVEN K U RES & DEV (BE) | 2011-08-31 | — | — | EP | disclosed |
| EP-2332938-A1 | Viral inhibitors | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2011-06-15 | — | — | EP | disclosed |
| US-7737162-B2 | Viral inhibitors | GILEAD SCIENCES, INC. (US) | 2010-06-15 | — | — | US | disclosed |
| US-20100004281-A1 | VIRAL INHIBITORS | GILEAD SCIENCES, INC. | 2010-01-07 | — | — | US | disclosed |
| US-20050239821-A1 | Viral inhibitors | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004281-A1 | VIRAL INHIBITORS | ZC3HAV1, MAVS, HAVCR2 | NPC1 607/4885RAB9A 1537/4885KMT2A 2253/4885 |
| US-20050239821-A1 | Viral inhibitors | ZC3HAV1, ZC3HAV1L, ACE | NPC1 562/4885RAB9A 2520/4885KMT2A 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.