SCHEMBL19600399

SCHEMBL19600399

c1ccc2cc(-c3ccc4c5c(cccc35)Oc3cc(-c5c6ccccc6cc6ccccc56)ccc3-4)ccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.41
MAPK1 P28482 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
ALOX5 P09917 3/20 0.38
GSTP1 P09211 1/20 0.36
CES1 P23141 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
ANPEP P15144 1/20 0.33
PDE9A O76083 1/20 0.33
NQO2 P16083 1/20 0.32
CYP1A2 P05177 2/20 0.32
TSHR P16473 2/20 0.32
HIF1A Q16665 2/20 0.32
MAOA P21397 2/20 0.32
ERBB2 P04626 1/20 0.32
FYN P06241 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19600404 0.88 KDM4E (0.40) GPR84MAPK1KDM4EATMALOX5
SCHEMBL17265414 0.88 GPR84 (0.39) GPR84MAPK1KDM4EATMALOX5
SCHEMBL16558425 0.87 MAPK1 (0.49) GPR84MAPK1KDM4EATMGSTP1
SCHEMBL16558417 0.86 MAPK1 (0.50) GPR84MAPK1KDM4EATMALOX5
SCHEMBL16558415 0.86 MAPK1 (0.48) GPR84MAPK1KDM4EATMGSTP1
SCHEMBL19600430 0.86 KDM4E (0.45) GPR84MAPK1KDM4EATMGSTP1
SCHEMBL22971969 0.86 MAPK1 (0.55) GPR84MAPK1KDM4EATMALOX5
SCHEMBL23109668 0.85 MAPK1 (0.50) GPR84MAPK1KDM4EATMALOX5
SCHEMBL15856983 0.84 MAPK1 (0.53) GPR84MAPK1KDM4EATMALOX5
SCHEMBL13507802 0.84 KDM4E (0.40) GPR84MAPK1KDM4EATMALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573825-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573825-B2 Compound and organic light-emitting device including the same CRY1, CRY2, AOX1 GPR84 2471/4885MAPK1 2174/4885KDM4E 2074/4885
US-20170331051-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, AOX1 GPR84 2471/4885MAPK1 2174/4885KDM4E 2074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.