SCHEMBL19600573

SCHEMBL19600573

C[Si](C)(C)c1ccc(CCNI)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.36
TMEM97 Q5BJF2 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
ATM Q13315 1/20 0.34
MAPT P10636 2/20 0.33
CYP1A2 P05177 2/20 0.33
TSHR P16473 2/20 0.33
NFKB1 P19838 2/20 0.33
TP53 P04637 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33
THPO P40225 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
F13A1 P00488 1/20 0.32
GMNN O75496 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6510336 0.79 ESR1 (0.41) TAAR1CYP1A2GFERNR1H2NR1H3
SCHEMBL23572283 0.76 ALDH1A1 (0.50) TAAR1MAPTCYP1A2ALOX15ALDH1A1
SCHEMBL3264156 0.73 LPL (0.46) MAPTALDH1A1KDM4EGFERCA2
SCHEMBL21675739 0.72 TAAR1 (0.47) TAAR1TMEM97SIGMAR1ATMMAPT
SCHEMBL15295135 0.71 TAAR1 (0.61) TAAR1MAPTSMN1; SMN2CA1CA2
SCHEMBL13218890 0.71 TMEM97 (0.61) TAAR1TMEM97SIGMAR1ALOX15HIF1A
SCHEMBL14824989 0.71 LOXL2 (0.50) CYP1A2HSD17B10ALDH1A1SMN1; SMN2KDM4E
SCHEMBL22330599 0.71 GFER (0.59) MAPTCYP1A2TSHRNFKB1ALDH1A1
SCHEMBL19600562 0.71 TAAR1 (0.56) TAAR1CYP1A2ALDH1A1SMN1; SMN2KDM4E
SCHEMBL6309545 0.71 CA2 (0.52) MAPTTSHRALDH1A1KDM4ECA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170330694-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL AND COMPOSITION FUJIFILM CORPORATION (JP) 2017-11-16 US disclosed