Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPA | P38571 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17078235 | 1.00 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078227 | 0.99 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078300 | 0.95 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078250 | 0.93 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078253 | 0.90 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078239 | 0.90 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL19607576 | 0.90 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL19584717 | 0.79 | LIPA (0.72) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17244724 | 0.75 | ALDH1A1 (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL22799434 | 0.72 | ABHD6 (1.00) | LIPAALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017194734-A1 | MEANS AND METHODS FOR TREATING MYCOBACTERIAL DISEASES | Technische Universität München (DE) | 2017-11-16 | — | — | WO | disclosed |