Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPA | P38571 | 8/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607575 | 1.00 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078227 | 0.99 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078300 | 0.95 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078250 | 0.93 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078253 | 0.90 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17078239 | 0.90 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL19607576 | 0.90 | LIPA (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL19584717 | 0.79 | LIPA (0.72) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL17244724 | 0.75 | ALDH1A1 (1.00) | LIPAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL22799434 | 0.72 | ABHD6 (1.00) | LIPAALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220090023-A1 | METHODS FOR REGULATING POTENCY OF PLURIPOTENT STEM CELLS AND APPLICATIONS THEREOF | ACADEMIA SINICA (TW) | 2022-03-24 | — | — | US | claimed |
| WO-2015135652-A1 | ANTAGONISTS OF ACID LIPASE FOR PREVENTING VIRUS INFECTION | Technische Universität München (DE) | 2015-09-17 | — | — | WO | claimed |
| WO-2025199564-A1 | AUTOPHAGY SENSORS | LA TROBE UNIVERSITY (AU) | 2025-10-02 | — | — | WO | disclosed |
| US-20250177341-A1 | DIETARY TRIPROPIONIN SUPPLEMENTATION TO REDUCE ADIPOSITY AND IMPROVE GLUCOSE HOMEOSTASIS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-06-05 | — | — | US | disclosed |
| WO-2025021839-A1 | METHOD TO TREAT METABOLIC DISORDERS | Institut National de la Santé et de la Recherche Médicale (FR) | 2025-01-30 | — | — | WO | disclosed |
| WO-2024197271-A1 | TARGETING LYSOSOMAL LIPID IN ALZHEIMER'S DISEASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2024-09-26 | — | — | WO | disclosed |
| US-20220226339-A1 | INHIBITATION OF ACID LIPASE FOR CANCER THERAPY | HEINRICH-HEINE-UNIVERSITÄT DÜSSELDORF (DE) | 2022-07-21 | — | — | US | disclosed |
| EP-3994276-A1 | INHIBITATION OF ACID LIPASE FOR CANCER THERAPY | Heinrich-Heine-Universität Düsseldorf (DE) | 2022-05-11 | — | — | EP | disclosed |
| US-20220090023-A1 | METHODS FOR REGULATING POTENCY OF PLURIPOTENT STEM CELLS AND APPLICATIONS THEREOF | ACADEMIA SINICA (TW) | 2022-03-24 | — | — | US | disclosed |
| WO-2017194734-A1 | MEANS AND METHODS FOR TREATING MYCOBACTERIAL DISEASES | Technische Universität München (DE) | 2017-11-16 | — | — | WO | disclosed |
| WO-2015135652-A1 | ANTAGONISTS OF ACID LIPASE FOR PREVENTING VIRUS INFECTION | Technische Universität München (DE) | 2015-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250177341-A1 | DIETARY TRIPROPIONIN SUPPLEMENTATION TO REDUCE ADIPOSITY AND IMPROVE GLUCOSE HOMEOSTASIS | GPR119, FABP4, MTPN | LIPA 1968/4885ALDH1A1 2876/4885MAPT 3849/4885 |
| US-20220226339-A1 | INHIBITATION OF ACID LIPASE FOR CANCER THERAPY | PNLIP, LPL, LIPA | LIPA 3/4885ALDH1A1 194/4885MAPT 4731/4885 |
| US-20220090023-A1 | METHODS FOR REGULATING POTENCY OF PLURIPOTENT STEM CELLS AND APPLICATIONS THEREOF | CDYL, ZFX, CDYL2 | LIPA 3983/4885ALDH1A1 1025/4885MAPT 4577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.