SCHEMBL22799434

SCHEMBL22799434

CN(C(=O)Oc1nsnc1N1CCOCC1)C1CCCCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ABHD6 Q9BV23 2/20 1.00
LIPA P38571 8/20 0.59
ALDH1A1 P00352 4/20 0.58
MAPT P10636 2/20 0.58
KDM4E B2RXH2 1/20 0.58
HPGD P15428 1/20 0.58
ALOX15 P16050 1/20 0.58
HSD17B10 Q99714 1/20 0.58
LMNA P02545 1/20 0.56
TSHR P16473 1/20 0.56
KMT2A Q03164 3/20 0.51
POLB P06746 1/20 0.51
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
MAPK1 P28482 1/20 0.43
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17078300 0.74 LIPA (1.00) ABHD6LIPAALDH1A1MAPTKDM4E
SCHEMBL17244724 0.74 ALDH1A1 (1.00) ABHD6LIPAALDH1A1MAPTKDM4E
SCHEMBL17078250 0.72 LIPA (1.00) ABHD6LIPAALDH1A1MAPTKDM4E
SCHEMBL17078235 0.72 LIPA (1.00) ABHD6LIPAALDH1A1MAPTKDM4E
SCHEMBL19607575 0.72 LIPA (1.00) ABHD6LIPAALDH1A1MAPTKDM4E
SCHEMBL17078227 0.70 LIPA (1.00) ABHD6LIPAALDH1A1MAPTKDM4E
SCHEMBL13953865 0.65 KMT2A (0.69) LIPAALDH1A1MAPTKDM4EHPGD
SCHEMBL4375383 0.64 MAPT (0.50) ABHD6ALDH1A1MAPTLMNAKMT2A
SCHEMBL19607576 0.64 LIPA (1.00) ABHD6LIPAALDH1A1MAPTKDM4E
SCHEMBL17078239 0.64 LIPA (1.00) ABHD6LIPAALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025017210-A1 MONOGLYCERIDE LIPASE INHIBITORS IN THE TREATMENT OF PANCREATIC CANCER KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-01-23 WO disclosed
WO-2023283977-A1 USE OF PREPARATION FOR INHIBITING OR BLOCKING INTERACTION BETWEEN FAAH AND NLRP3 华南理工大学 2023-01-19 WO disclosed
CN-115616216-A Use of an agent that inhibits or blocks the interaction between FAAH and NLRP3 华南理工大学 2023-01-17 CN disclosed
EP-3587554-B1 METHOD FOR ACCELERATED DETERMINATION OF THE CONCENTRATION OF LIVING THERMOPHILIC BACTERIA IN WATER-BEARING INSTALLATIONS INWATEC GMBH & CO KG (DE) 2020-12-23 EP disclosed