Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22825659 | 0.98 | LMNA (0.42) | ALDH1A1LMNALTB4RLTB4R2USP2 | |
| SCHEMBL29842192 | 0.93 | LMNA (0.42) | ALDH1A1LMNALTB4RLTB4R2MEN1 | |
| SCHEMBL18603087 | 0.81 | LTB4R (0.40) | ALDH1A1LMNALTB4RLTB4R2USP2 | |
| SCHEMBL26880817 | 0.79 | CYP1A2 (0.56) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19609971 | 0.79 | ALDH1A1 (0.38) | ALDH1A1LMNALTB4RLTB4R2USP2 | |
| SCHEMBL13212895 | 0.77 | LMNA (0.62) | ALDH1A1LMNAUSP2MEN1KMT2A | |
| SCHEMBL26880353 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4005530 | 0.77 | CA2 (0.45) | LMNAMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL21004727 | 0.77 | ALDH1A1 (0.37) | ALDH1A1LMNALTB4RLTB4R2USP2 | |
| SCHEMBL15821676 | 0.76 | LMNA (0.39) | LMNAMEN1KMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020253762-A1 | INDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2020-12-24 | — | — | WO | disclosed |
| US-20100210652-A1 | Method For Controlling Fungal Pests | BASF SE (DE) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210652-A1 | Method For Controlling Fungal Pests | CBR3, CAT, CYCS | ALDH1A1 2074/4885LMNA 1516/4885LTB4R 4191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.