Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 6/20 | 0.37 |
| ▸ | THRB | P10828 | 6/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19610487 | 0.88 | FABP3 (0.46) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL20681236 | 0.87 | FABP3 (0.43) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL19610490 | 0.86 | CA1 (0.46) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL20699064 | 0.84 | KDM4E (0.44) | FABP3FABP4GAAKDM4ETHRA | |
| SCHEMBL19475246 | 0.82 | GABRA1 (0.50) | FABP3FABP4GAAKDM4EGABRA1 | |
| SCHEMBL19475203 | 0.82 | NLRP3 (0.41) | FABP3FABP4GAAKDM4EAGBL2 | |
| SCHEMBL20681232 | 0.82 | GABRA1 (0.50) | FABP3FABP4GAAKDM4EGABRA1 | |
| SCHEMBL8136292 | 0.82 | FABP4 (0.50) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL23319820 | 0.81 | THRB (0.40) | FABP3FABP4GAAKDM4EGABRA1 | |
| SCHEMBL7207662 | 0.81 | FABP4 (0.58) | FABP3FABP4SOAT2MYCSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057169-B | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| US-6093744-A | USE AS CEREBROVASCULAR AGENTS IN DISEASES SUCH AS STROKE, PERIPHERAL VASCULAR DISEASE, RESTENOSIS, AND AS AGENTS FOR REGULATING PLASMA CHOLESTEROL CONCENTRATIONS, FOR TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 2000-07-25 | — | — | US | disclosed |
| US-6017905-A | TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0698010-B1 | N-ACYL SULFAMIC ACID ESTERS (OR THIOESTERS), N-ACYL SULFONAMIDES, AND N-SULFONYL CARBAMIC ACID ESTERS (OR THIOESTERS) AS HYPERCHOLESTEROLEMIC AGENTS | WARNER LAMBERT CO (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5807846-A | TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| WO-1994026702-A1 | N-ACYL SULFAMIC ACID ESTERS (OR THIOESTERS), N-ACYL SULFONAMIDES, AND N-SULFONYL CARBAMIC ACID ESTERS (OR THIOESTERS) AS HYPERCHOLESTEROLEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |