Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 10/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.46 |
| ▸ | SCN1A | P35498 | 9/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 9/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720161 | 0.80 | SCN1A (0.48) | SCN9ASCN5ASCN1ASCN8ASLC22A12 | |
| SCHEMBL22634311 | 0.80 | KMT2A (0.54) | SCN9ASCN5ASCN1ASCN8A | |
| SCHEMBL1093964 | 0.78 | SCN1A (0.54) | SCN9ASCN5ASCN1ASCN8ANR1I2 | |
| SCHEMBL1095602 | 0.76 | GLO1 (0.53) | SCN9ASCN5ASCN1ASCN8ASLC22A12 | |
| Formic Acid SCHEMBL19616986 | 0.75 | SCN1A (0.49) | SCN9ASCN5ASCN1ASCN8ANR1I2 | |
| SCHEMBL3477271 | 0.72 | SLC40A1 (0.50) | SCN9ASCN5ASCN1ASCN8A | |
| SCHEMBL11704625 | 0.70 | SMN1; SMN2 (0.56) | SCN9ASCN5ASCN1ASCN8ACYP2C9 | |
| SCHEMBL29669168 | 0.69 | SCN1A (0.57) | SCN9ASCN5ASCN1ASCN8ASLC22A12 | |
| SCHEMBL19613699 | 0.69 | SCN1A (0.57) | SCN9ASCN5ASCN1ASCN8ASLC22A12 | |
| SCHEMBL19613818 | 0.69 | SCN1A (0.58) | SCN9ASCN5ASCN1ASCN8ASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | claimed |
| EP-3458449-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2019-03-27 | — | — | EP | disclosed |
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | disclosed |
| WO-2017201468-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2017-11-23 | — | — | WO | disclosed |