Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 9/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 9/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 8/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22634311 | 0.83 | KMT2A (0.54) | SCN1ASCN8ASCN9ASCN5A | |
| SCHEMBL1093964 | 0.82 | SCN1A (0.54) | SCN1ASCN8ASCN9ASCN5APKM | |
| SCHEMBL1095602 | 0.80 | GLO1 (0.53) | SCN1ASCN8ASCN9ASCN5ASLC22A12 | |
| SCHEMBL19617682 | 0.80 | SCN9A (0.46) | SCN1ASCN8ASCN9ASCN5ASLC22A12 | |
| Formic Acid SCHEMBL19616986 | 0.78 | SCN1A (0.49) | SCN1ASCN8ASCN9ASCN5AKAT6A | |
| SCHEMBL3477271 | 0.75 | SLC40A1 (0.50) | SCN1ASCN8ASCN9ASCN5ACA2 | |
| SCHEMBL16720330 | 0.73 | SCN8A (0.36) | SCN1ASCN8ASCN9ASCN5ANR1I2 | |
| SCHEMBL11704625 | 0.73 | SMN1; SMN2 (0.56) | SCN1ASCN8ASCN9ASCN5ACYP2C9 | |
| SCHEMBL28541158 | 0.72 | HSD11B1 (0.53) | PKM | |
| SCHEMBL19613699 | 0.72 | SCN1A (0.57) | SCN1ASCN8ASCN9ASCN5ASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |