Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14874963 | 0.68 | — | — | |
| SCHEMBL3433755 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL8992422 | 0.67 | OPRM1 (0.43) | HPGDEPHX2MAPK1P2RX7MEN1 | |
| SCHEMBL1961831 | 0.66 | DDB1 (0.43) | — | |
| SCHEMBL1347780 | 0.65 | OPRM1 (0.46) | HPGDEPHX1ALDH1A1USP2MEN1 | |
| SCHEMBL3432957 | 0.65 | — | — | |
| SCHEMBL572229 | 0.64 | OPRM1 (0.55) | HPGDEPHX1MEN1KMT2ARAB9A | |
| SCHEMBL12491992 | 0.64 | MMP8 (0.57) | HPGDEPHX1ALDH1A1USP2MEN1 | |
| Hydrochloric Acid SCHEMBL573397 | 0.63 | OPRM1 (0.56) | HPGDEPHX1MEN1KMT2ARAB9A | |
| SCHEMBL27797781 | 0.61 | GRIN2B (0.56) | HPGDEPHX1ALDH1A1USP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946413-B2 | 3-aminocyclopentanecarboxamides as chemokine receptor agonists | PFIZER INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-20110144129-A1 | 3-Aminocyclopentanecarboxamides as Chemokine Receptor Agonists | PFIZER INC | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144129-A1 | 3-Aminocyclopentanecarboxamides as Chemokine Receptor Agonists | ACKR3, CCR2, CCR5 | HPGD 1342/4885EPHX1 1146/4885ALDH1A1 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.