Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17242431 | 0.76 | MAPT (0.36) | MAPTROCK1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL25060367 | 0.74 | EGFR (0.44) | SMN1; SMN2KMT2A | |
| SCHEMBL19533519 | 0.71 | GLS (0.38) | MAPTSMN1; SMN2NOS1LMNACYP3A4 | |
| SCHEMBL15831285 | 0.71 | ROCK1 (0.65) | MAPTROCK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL19533520 | 0.70 | FGFR1 (0.54) | MAPTSMN1; SMN2RPS6KA5HTTALDH1A1 | |
| SCHEMBL29929291 | 0.68 | MAPT (0.41) | MAPTSMN1; SMN2LMNAPOLBRPS6KA5 | |
| SCHEMBL26977540 | 0.68 | MAPT (0.41) | MAPTSMN1; SMN2LMNAPOLBRPS6KA5 | |
| SCHEMBL2160271 | 0.65 | ALDH1A1 (0.46) | MAPTSMN1; SMN2HTTALDH1A1KMT2A | |
| SCHEMBL26934237 | 0.65 | ALDH1A1 (0.46) | MAPTSMN1; SMN2CYP3A4HTTALDH1A1 | |
| SCHEMBL17242433 | 0.65 | NPC1 (0.35) | MAPTKMT2APIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |