Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ESPL1 | Q14674 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26934237 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ESPL1GAACAPN9 | |
| SCHEMBL7036155 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ESPL1GAACAPN9 | |
| SCHEMBL7033977 | 0.74 | SIRT2 (0.46) | ALDH1A1SMN1; SMN2ESPL1GAAMAPT | |
| SCHEMBL7030960 | 0.74 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GAAMAPTPNMT | |
| SCHEMBL7035376 | 0.74 | MAPT (0.42) | ALDH1A1SMN1; SMN2ESPL1GAACAPN9 | |
| SCHEMBL28743060 | 0.72 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2ESPL1GAACAPN9 | |
| SCHEMBL7029422 | 0.72 | CASP1 (0.48) | ALDH1A1SMN1; SMN2GAACASP3MAPT | |
| SCHEMBL7034434 | 0.70 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2ESPL1GAAMAPT | |
| SCHEMBL24982 | 0.69 | MAPT (0.49) | ALDH1A1CAPN9CASP3MAPTPNMT | |
| SCHEMBL200716 | 0.69 | PNMT (0.58) | ALDH1A1CAPN9CASP3MAPTPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985771-B2 | Skin disorders; aging resistance | MONSANTO TECHNOLOGY LLC (US) | 2011-07-26 | — | — | US | disclosed |
| EP-1660080-A1 | FURANONE DERIVATIVES | Galileo Pharmaceuticals, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1478634-A4 | FURANONE DERIVATIVES | GALILEO PHARMACEUTICALS INC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2005016340-A1 | FURANONE DERIVATIVES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| EP-1478634-A1 | FURANONE DERIVATIVES | Galileo Pharmaceuticals, Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040029812-A1 | Furanone derivatives | MONSANTO TECHNOLOGY LLC | 2004-02-12 | — | — | US | disclosed |
| US-6667330-B2 | Cytoprotective; neuroinflammation and neurodegenerative disorders; oxidative stress related conditions | GALILEO PHARMACEUTICALS, INC. | 2003-12-23 | — | — | US | disclosed |
| US-20030176361-A1 | Furanone derivatives | MONSANTO TECHNOLOGY LLC | 2003-09-18 | — | — | US | disclosed |
| WO-2003064403-A1 | FURANONE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176361-A1 | Furanone derivatives | HSPA9, HSF1, IL1B | ALDH1A1 903/4885SMN1; SMN2 107/4885ESPL1 4561/4885 |
| US-20040029812-A1 | Furanone derivatives | TNF, PPIF, NOX5 | ALDH1A1 944/4885SMN1; SMN2 4849/4885ESPL1 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.