Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187238 | 0.82 | L3MBTL1 (0.55) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL18773876 | 0.81 | TRPM8 (0.46) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL427048 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL14004817 | 0.80 | FNTA (0.53) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL17468873 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL7326927 | 0.79 | CYP1A2 (0.45) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL27549223 | 0.79 | TRPM8 (0.44) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL9529185 | 0.78 | PTPRA (0.50) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL6170953 | 0.78 | TRPM8 (0.59) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 | |
| SCHEMBL21994253 | 0.77 | MAPT (0.52) | SMN1; SMN2TDP1MAPTLIN28ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838519-B1 | METHODS AND COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS AND VIRAL INFECTIONS | UNIV COLLEGE DUBLIN NAT UNIV OF IRELAND DUBLIN (IE) | 2017-11-22 | — | — | EP | disclosed |