Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19625142 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL18773876 | 0.74 | TRPM8 (0.46) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL13470280 | 0.72 | ALDH1A1 (0.59) | SMN1; SMN2MAPTTDP1ALDH1A1RAB9A | |
| SCHEMBL27549223 | 0.72 | TRPM8 (0.44) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL12204158 | 0.70 | TRPM8 (0.60) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL2187238 | 0.70 | L3MBTL1 (0.55) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL7326927 | 0.69 | CYP1A2 (0.45) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL9529185 | 0.69 | PTPRA (0.50) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL12313339 | 0.69 | NTRK1 (0.51) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL6170953 | 0.69 | TRPM8 (0.59) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012362-A1 | SUBSTITUTED CYANO CYCLOALKYL PENTA-2,4-DIENES, CYANO CYCLOALKYL PENT-2-EN-4-YNES, CYANO HETEROCYCLYL PENTA-2,4-DIENES AND CYANO HETEROCYCLYL PENT-2-EN-4-YNES AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-28 | — | — | WO | disclosed |