Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15170931 | 0.83 | SMN1; SMN2 (0.45) | PTPRAKCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL2187238 | 0.81 | L3MBTL1 (0.55) | PTPRAKCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL427048 | 0.79 | SMN1; SMN2 (0.52) | PTPRAKCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL6204342 | 0.79 | KDM4E (0.52) | PTPRAKCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL7657030 | 0.79 | PTPRA (0.40) | PTPRAKCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL28923770 | 0.79 | L3MBTL1 (0.60) | PTPRAKCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL27718450 | 0.79 | KCNA5 (0.47) | PTPRAKCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL19625142 | 0.78 | SMN1; SMN2 (0.50) | PTPRAKCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL2961946 | 0.77 | CYP1A2 (0.54) | PTPRAKCNA5SMN1; SMN2MAPTLIN28A | |
| SCHEMBL6170953 | 0.77 | TRPM8 (0.59) | KCNA5SMN1; SMN2MAPTLIN28ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | claimed |