Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19626314 | 0.78 | ALDH1A1 (0.34) | KDM4EHSD17B10ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL19626312 | 0.76 | MEN1 (0.33) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19677950 | 0.74 | KDM4E (0.42) | KDM4ENPSR1HSD17B10KDM5APDE2A | |
| SCHEMBL19036912 | 0.71 | KDM4E (0.41) | KDM4ENPSR1HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL19680297 | 0.69 | LMNA (0.54) | KDM4ENPSR1HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL20348410 | 0.69 | HSD17B10 (0.45) | KDM4ENPSR1HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL14033000 | 0.63 | MAPT (0.32) | KDM4ENPSR1HSD17B10KDM5AALDH1A1 | |
| SCHEMBL14033224 | 0.62 | MTNR1A (0.36) | KDM4ENPSR1HSD17B10PDE2AALDH1A1 | |
| SCHEMBL13472665 | 0.62 | KDM4E (0.37) | KDM4ENPSR1HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL18179934 | 0.62 | ALDH1A1 (0.40) | KDM4ENPSR1HSD17B10ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170333435-A1 | SUBSTITUTED IMIDAZO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL - BIOTECH INVESTMENTS, INC. (PT) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170333435-A1 | SUBSTITUTED IMIDAZO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | GAA, GBA1, PARK7 | KDM4E 710/4885NPSR1 3305/4885HSD17B10 4662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.