Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11953212 | 0.86 | NPC1 (0.65) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL3001175 | 0.78 | SMN1; SMN2 (0.64) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL11517284 | 0.77 | MAPT (0.68) | RAB9ASMN1; SMN2HPGDALDH1A1CA12 | |
| SCHEMBL15143918 | 0.74 | SMN1; SMN2 (0.79) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL22071184 | 0.73 | TP53 (0.48) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL7278525 | 0.73 | ALDH1A1 (0.71) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 | |
| SCHEMBL243401 | 0.72 | CYP17A1 (0.56) | ALDH1A1CA12CA2CA9EPHX2 | |
| SCHEMBL12369268 | 0.72 | MITF (0.64) | RAB9ASMN1; SMN2NPC1HPGDLMNA | |
| SCHEMBL10668920 | 0.72 | RAB9A (0.64) | RAB9ASMN1; SMN2NPC1HPGDCYP2D6 | |
| SCHEMBL8052997 | 0.72 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2NPC1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350315-B2 | Quinoline-3-carboxamide compounds and their use in diagnosis | Westfaelische Wihelms-Universitaet Muenster (DE) | 2019-07-16 | — | — | US | disclosed |
| US-20170333577-A1 | QUINOLINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE IN DIAGNOSIS | Westfälische Wilhelms-Universität Münster (DE) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10350315-B2 | Quinoline-3-carboxamide compounds and their use in diagnosis | S100A9, S100A4, S100A10 | RAB9A 154/4885SMN1; SMN2 3694/4885NPC1 3035/4885 |
| US-20170333577-A1 | QUINOLINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE IN DIAGNOSIS | S100A9, S100A4, S100A10 | RAB9A 154/4885SMN1; SMN2 3694/4885NPC1 3035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.