Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 4/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633784 | 0.84 | KIF11 (0.53) | CYP1A2HTTTDP1PARP14KMT2A | |
| SCHEMBL18669851 | 0.78 | CA2 (0.63) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL20887130 | 0.77 | KIF11 (0.58) | CYP1A2PARP14KMT2AKDM4ETSHR | |
| SCHEMBL27613656 | 0.76 | CA2 (0.64) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL11127453 | 0.76 | CA2 (0.64) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL28234384 | 0.75 | FEN1 (0.57) | CYP1A2PARP14KMT2AKDM4ETSHR | |
| SCHEMBL28851832 | 0.73 | FEN1 (0.59) | CYP1A2L3MBTL1PARP14KMT2AKDM4E | |
| SCHEMBL636439 | 0.73 | CA2 (0.69) | CA2CYP1A2CYP2C19HTTHIF1A | |
| SCHEMBL329710 | 0.73 | KIF11 (0.52) | CYP1A2HTTTDP1PARP14KMT2A | |
| SCHEMBL17294738 | 0.72 | CA2 (0.55) | CA2CYP1A2CYP2C19HTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186820-B | Fluorescent regulators of rassf1a expression and human cancer cell proliferation | UNIV GEORGETOWN | 2013-08-28 | — | — | CN | claimed |
| EP-2323982-B1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | UNIV GEORGETOWN (US) | 2012-02-29 | — | — | EP | claimed |
| JP-2012500197-A | — | — | 2012-01-05 | — | — | JP | claimed |
| CN-102186820-A | Fluorescent regulators of rassf1a expression and human cancer cell proliferation | UNIV GEORGETOWN | 2011-09-14 | — | — | CN | claimed |
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY | 2011-06-23 | — | — | US | claimed |
| EP-2323982-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | Georgetown University (US) | 2011-05-25 | — | — | EP | claimed |
| WO-2010019271-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY (US) | 2010-02-18 | — | — | WO | claimed |
| US-10457639-B2 | Fluorescent regulators of RASSF1A expression and human cancer cell proliferation | GEORGETOWN UNIVERSITY (US) | 2019-10-29 | — | — | US | disclosed |
| US-10457639-B2 | Fluorescent regulators of RASSF1A expression and human cancer cell proliferation | GEORGETOWN UNIVERSITY (US) | 2019-10-29 | — | — | US | disclosed |
| US-8637679-B2 | Process for the isolation of organic compounds useful for the treatment of cancer | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-01-28 | — | — | US | disclosed |
| CN-102186820-B | Fluorescent regulators of rassf1a expression and human cancer cell proliferation | UNIV GEORGETOWN | 2013-08-28 | — | — | CN | disclosed |
| CN-102186820-B | Fluorescent regulators of rassf1a expression and human cancer cell proliferation | UNIV GEORGETOWN | 2013-08-28 | — | — | CN | disclosed |
| US-20130065932-A1 | PROCESS FOR THE ISOLATION OF ORGANIC COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2013-03-14 | — | — | US | disclosed |
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY | 2011-06-23 | — | — | US | disclosed |
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY | 2011-06-23 | — | — | US | disclosed |
| EP-2323982-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | Georgetown University (US) | 2011-05-25 | — | — | EP | disclosed |
| EP-2323982-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | Georgetown University (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010019271-A8 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY (US) | 2011-03-31 | — | — | WO | disclosed |
| WO-2010019271-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY (US) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010019271-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | GEORGETOWN UNIVERSITY (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152339-A1 | FLUORESCENT REGULATORS OF RASSF1A EXPRESSION AND HUMAN CANCER CELL PROLIFERATION | RASSF5, RASSF2, MKI67 | CA2 3199/4885CYP1A2 3607/4885CYP2C19 3781/4885 |
| US-20130065932-A1 | PROCESS FOR THE ISOLATION OF ORGANIC COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER | PSMG3, HSP90B1, HSPA1A | CA2 3567/4885CYP1A2 1411/4885CYP2C19 2542/4885 |
| US-10457639-B2 | Fluorescent regulators of RASSF1A expression and human cancer cell proliferation | RASSF5, RASSF2, MKI67 | CA2 3199/4885CYP1A2 3607/4885CYP2C19 3781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.