Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KDM6B | O15054 | 2/20 | 0.53 |
| ▸ | KDM5C | P41229 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TET3 | O43151 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | ASPH | Q12797 | 1/20 | 0.53 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.53 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.53 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.53 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19632064 | 0.84 | MITF (0.51) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL19631986 | 0.84 | MITF (0.51) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL19632157 | 0.84 | KDM4C (0.57) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL8806581 | 0.82 | CES2 (0.65) | KDM4EMRGPRX4CYP2C8CES2CES1 | |
| SCHEMBL6827745 | 0.82 | CES2 (0.74) | KDM4EMRGPRX4CYP2C8CES2CES1 | |
| SCHEMBL29351426 | 0.82 | CES2 (0.74) | KDM4EMRGPRX4CYP2C8CES2CES1 | |
| SCHEMBL63427 | 0.82 | CES2 (0.74) | KDM4EMRGPRX4CYP2C8CES2CES1 | |
| SCHEMBL7547074 | 0.81 | RAB9A (0.64) | CNR2KDM4EALDH1A1MAPTCES2 | |
| SCHEMBL5762817 | 0.80 | KDM4C (0.69) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL10403563 | 0.80 | CES2 (0.71) | KDM4EMRGPRX4CYP2C8CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198785-A1 | OXIME DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASE KDM4C | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |