Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 2/20 | 0.38 |
| ▸ | CCR8 | P51685 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22053002 | 0.88 | HTR7 (0.34) | TDP1KDM4EL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL28479920 | 0.83 | NPC1 (0.49) | TDP1KDM4EL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL31345430 | 0.82 | CTSS (0.41) | — | |
| SCHEMBL2816133 | 0.78 | KDM4E (0.56) | TDP1KDM4EL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL8731856 | 0.77 | RAB9A (0.45) | TDP1KDM4ESMN1; SMN2ALOX15LMNA | |
| SCHEMBL150058 | 0.71 | — | — | |
| SCHEMBL2655553 | 0.70 | NPC1 (0.46) | KDM4EL3MBTL1SMN1; SMN2ALOX15MAPK1 | |
| SCHEMBL10896312 | 0.70 | NISCH (0.41) | TDP1KDM4EL3MBTL1SMN1; SMN2ALPL | |
| SCHEMBL10759273 | 0.69 | CLK4 (0.32) | — | |
| SCHEMBL155254 | 0.67 | METAP2 (0.36) | TDP1KDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681228-B1 | PLATINUM COMPLEXES AND THEIR USE | Westfälische Wilhelms-Universität Münster (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-20130004986-A1 | Use of luminescent Ir(III) and Ru(II) complexes | WESTFAELISCHE WILHELMS-UNIVERITAET MUENSTER (DE) | 2013-01-03 | — | — | US | disclosed |
| EP-2507339-A1 | USE OF LUMINESCENT IR(III) AND RU(II) COMPLEXES | Westfälische Wilhelms-Universität Münster (DE) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067401-A1 | USE OF LUMINESCENT IR(III) AND RU(II) COMPLEXES | Westfälische Wilhelms-Universität Münster (DE) | 2011-06-09 | — | — | WO | disclosed |