Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337201 | 0.87 | CHRNA7 (0.35) | TRPV4P2RX7MLYCD | |
| SCHEMBL485040 | 0.87 | TRPV4 (0.48) | TRPV4P2RX7 | |
| SCHEMBL14878749 | 0.86 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL1961117 | 0.85 | SMN1; SMN2 (0.33) | P2RX7 | |
| SCHEMBL12578908 | 0.84 | TRPV4 (0.37) | TRPV4P2RX7 | |
| SCHEMBL14260285 | 0.84 | TRPV4 (0.33) | TRPV4P2RX7 | |
| SCHEMBL1961161 | 0.84 | PTPN5 (0.35) | TRPV4P2RX7MLYCD | |
| SCHEMBL1961057 | 0.81 | TRPV4 (0.32) | TRPV4 | |
| SCHEMBL18405322 | 0.80 | TRPV4 (0.31) | TRPV4 | |
| SCHEMBL13285390 | 0.78 | TRPV4 (0.30) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3120701-B1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-2338882-B1 | 2-((6-(Haloalkyl substituted))pyridin-3-yl)-tetrahydro-1H-1(lamba)4-thien-1-ylidenecyanamide derivatives and related compounds as pesticides and insecticides | DOW AGROSCIENCES LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| EP-2338882-B1 | 2-((6-(Haloalkyl substituted))pyridin-3-yl)-tetrahydro-1H-1(lamba)4-thien-1-ylidenecyanamide derivatives and related compounds as pesticides and insecticides | DOW AGROSCIENCES LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| EP-3120701-A1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | Dow AgroSciences LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| EP-2369935-B1 | STABLE INSECTICIDE COMPOSITIONS AND METHODS FOR PRODUCING SAME | DOW AGROSCIENCES LLC (US) | 2016-07-27 | — | — | EP | disclosed |
| EP-2369921-B1 | STABLE SULFOXIMINE-INSECTICIDE COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-07-27 | — | — | EP | disclosed |
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-9125412-B2 | Stable insecticide compositions and methods for producing same | DOW AGROSCIENCES LLC (US) | 2015-09-08 | — | — | US | disclosed |
| US-9012654-B2 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)-alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2015-04-21 | — | — | US | disclosed |
| US-20080280915-A1 | Insecticidal n-substituted (heteroaryl)alkyl sulfilimines | CORTEVA AGRISCIENCE LLC | 2008-11-13 | — | — | US | disclosed |
| US-20080280915-A1 | Insecticidal n-substituted (heteroaryl)alkyl sulfilimines | CORTEVA AGRISCIENCE LLC | 2008-11-13 | — | — | US | disclosed |
| EP-1989184-A2 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | Dow AgroSciences LLC (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2008030266-A2 | INSECTICIDAL N-SUBSTITUTED (HETEROARYL)ALKYL SULFILMINES | DOW AGROSCIENCES LLC (US) | 2008-03-13 | — | — | WO | disclosed |
| WO-2008030266-A2 | INSECTICIDAL N-SUBSTITUTED (HETEROARYL)ALKYL SULFILMINES | DOW AGROSCIENCES LLC (US) | 2008-03-13 | — | — | WO | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | CORTEVA AGRISCIENCE LLC | 2007-08-30 | — | — | US | disclosed |
| WO-2007095229-A2 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007095229-A2 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2007-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280915-A1 | Insecticidal n-substituted (heteroaryl)alkyl sulfilimines | AANAT, GNMT, STS | TRPV4 4208/4885P2RX7 2959/4885MLYCD 1981/4885 |
| US-20070203191-A1 | Insecticidal N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | NPEPPS, PRDX6, HDHD5 | TRPV4 1575/4885P2RX7 2038/4885MLYCD 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.