Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633482 | 0.84 | LMNA (0.40) | LMNAKMT2AFAAHACACBHTR7 | |
| SCHEMBL19633477 | 0.83 | LMNA (0.43) | LMNAKMT2AFAAHACACBHTR7 | |
| SCHEMBL17760970 | 0.81 | PPARG (0.41) | LMNAALDH1A1PPARAPPARG | |
| SCHEMBL19614771 | 0.81 | PPARG (0.41) | LMNAALDH1A1PPARAPPARG | |
| SCHEMBL19633411 | 0.81 | TRPA1 (0.41) | LMNAKMT2AFAAHACACBHTR7 | |
| SCHEMBL19633479 | 0.80 | FAAH (0.36) | LMNAKMT2AFAAHACACBPPARD | |
| SCHEMBL17905083 | 0.76 | TRPA1 (0.36) | LMNAKMT2AFAAHACACBHTR7 | |
| SCHEMBL12135751 | 0.69 | FAAH (0.45) | LMNAFAAHACACBHTR7HPGD | |
| SCHEMBL19633579 | 0.68 | ALDH1A1 (0.38) | LMNAKMT2AACACBHPGDHDAC3 | |
| SCHEMBL19628380 | 0.68 | TRPA1 (0.47) | KMT2AHPGDMAOBALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | LMNA 4285/4885KMT2A 3234/4885FAAH 1381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.