Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.49 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633815 | 0.93 | MEN1 (0.51) | MAPTKMT2AMEN1CYP19A1CYP11B1 | |
| SCHEMBL19633692 | 0.85 | CCNC (0.50) | MAPTKMT2AMEN1CYP19A1CYP11B1 | |
| SCHEMBL19633545 | 0.84 | KMT2A (0.49) | KMT2AMEN1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL19633797 | 0.76 | CYP19A1 (0.47) | MAPTKMT2AMEN1CYP19A1CYP11B1 | |
| SCHEMBL19633503 | 0.76 | GAK (0.53) | HTTGAKRIPK2COQ8ANLK | |
| SCHEMBL19633549 | 0.74 | KMT2A (0.55) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL1157681 | 0.73 | CYP19A1 (0.62) | MAPTKMT2AMEN1CYP19A1CYP11B1 | |
| SCHEMBL19633574 | 0.73 | CTSV (0.56) | MAPTKMT2AMEN1CCNCCDK8 | |
| SCHEMBL26086283 | 0.73 | GAK (0.59) | ALDH1A1POLBGAKRIPK2COQ8A | |
| SCHEMBL19633777 | 0.73 | GAK (0.57) | KMT2ALMNAALDH1A1GAKRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |