Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257936 | 0.82 | CHRNB2 (0.59) | CYP19A1CYP11B1CYP11B2CHRNB2CHRNA4 | |
| SCHEMBL19633545 | 0.81 | KMT2A (0.49) | CYP19A1CYP11B1CYP11B2CCNCCDK8 | |
| SCHEMBL19633577 | 0.80 | KDR (0.50) | CYP19A1PDGFRAKDR | |
| SCHEMBL12003929 | 0.79 | CTSV (0.50) | CYP19A1CYP11B1CYP11B2PDGFRAKDR | |
| SCHEMBL19633688 | 0.78 | KDR (0.52) | PDGFRAKDR | |
| SCHEMBL19633823 | 0.78 | PDGFRA (0.52) | PDGFRAKDR | |
| SCHEMBL7461659 | 0.78 | KDR (0.48) | PDGFRAKDRABCG2LMNAKMT2A | |
| SCHEMBL3976278 | 0.77 | CHRNB2 (0.57) | CYP19A1CYP11B1CYP11B2CHRNB2CHRNA4 | |
| SCHEMBL19633628 | 0.77 | PDGFRA (0.53) | PDGFRAKDRMEN1LMNAKMT2A | |
| SCHEMBL19633692 | 0.77 | CCNC (0.50) | CYP19A1CYP11B1CYP11B2CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |