Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 3/20 | 0.56 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 6/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633678 | 0.86 | PTK6 (0.56) | PTK6ERBB2GAAALDH1A1KMT2A | |
| SCHEMBL19633704 | 0.86 | PTK6 (0.66) | PTK6ERBB2GAAALDH1A1KMT2A | |
| SCHEMBL19633804 | 0.86 | FADS1 (0.56) | PTK6ERBB2GAAALDH1A1KMT2A | |
| SCHEMBL19633656 | 0.83 | AKR1C3 (0.58) | PTK6ERBB2KMT2AABCG2EGFR | |
| SCHEMBL19633684 | 0.81 | KMT2A (0.64) | PTK6ERBB2GAAALDH1A1KMT2A | |
| SCHEMBL19633574 | 0.81 | CTSV (0.56) | PTK6ERBB2GAAALDH1A1KMT2A | |
| SCHEMBL19633806 | 0.80 | KMT2A (0.51) | PTK6ERBB2GAAALDH1A1KMT2A | |
| SCHEMBL19633549 | 0.79 | KMT2A (0.55) | PTK6ERBB2GAAALDH1A1KMT2A | |
| SCHEMBL19633891 | 0.79 | ALK (0.68) | PKMYT1RETERBB2GAAMAPT | |
| SCHEMBL31167325 | 0.79 | PKMYT1 (0.60) | PKMYT1RETGAAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |