Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633823 | 0.91 | PDGFRA (0.52) | KDRPDGFRAMAOBAURKAMET | |
| SCHEMBL19633706 | 0.91 | PDGFRA (0.57) | KDRPDGFRAMAOBMET | |
| SCHEMBL19633577 | 0.90 | KDR (0.50) | KDRPDGFRAMAOBAURKAMET | |
| SCHEMBL19633697 | 0.86 | GAK (0.53) | KDRPDGFRAAURKAMETTEK | |
| SCHEMBL19633777 | 0.84 | GAK (0.57) | KDRPDGFRAEGFR | |
| SCHEMBL7482913 | 0.80 | PDGFRA (0.68) | KDRPDGFRAEGFR | |
| SCHEMBL19633698 | 0.80 | TUBB1 (0.57) | METEGFR | |
| SCHEMBL19633797 | 0.78 | CYP19A1 (0.47) | KDRPDGFRA | |
| SCHEMBL12003929 | 0.77 | CTSV (0.50) | KDRPDGFRAMAOB | |
| SCHEMBL19633713 | 0.76 | GAK (0.49) | KDRPDGFRAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |