Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RASGRP3 | Q8IV61 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899546 | 1.00 | ATM (0.51) | ATML3MBTL1RASGRP3MEN1KMT2A | |
| SCHEMBL3903585 | 1.00 | ATM (0.51) | ATML3MBTL1RASGRP3MEN1KMT2A | |
| SCHEMBL7182746 | 0.88 | ESR1 (0.43) | MEN1KMT2AMAPK1ALDH1A1PRKCA | |
| SCHEMBL25440024 | 0.84 | ADRB2 (0.51) | ATML3MBTL1RASGRP3MEN1KMT2A | |
| SCHEMBL27522136 | 0.82 | MAPT (0.46) | KMT2AMAPK1ALDH1A1MAPT | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL1500579 | 0.77 | KCNJ1 (0.68) | ATML3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL813536 | 0.76 | KMT2A (0.71) | ATML3MBTL1MEN1KMT2AMAPK1 | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL21644730 | 0.76 | KCNJ1 (0.64) | ATML3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL10439554 | 0.76 | ADRB2 (0.68) | ATML3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL7187426 | 0.75 | ALDH1A1 (0.45) | ATML3MBTL1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323990-B1 | METHODS FOR THE PRODUCTION OF 2-HALO-4-NITROIMIDAZOLE AND INTERMEDIATES THEREOF | DYNAMIT NOBEL AG (DE) | 2014-06-18 | — | — | EP | claimed |
| US-8558005-B2 | Methods for the production of 2-halo-4-nitroimidazole and intermediates thereof | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) | 2013-10-15 | — | — | US | claimed |
| JP-2012500183-A | — | — | 2012-01-05 | — | — | JP | claimed |
| US-20110178308-A1 | METHODS FOR THE PRODUCTION OF 2-HALO-4-NITROIMIDAZOLE AND INTERMEDIATES THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-07-21 | — | — | US | claimed |
| EP-2323990-A1 | METHODS FOR THE PRODUCTION OF 2-HALO-4-NITROIMIDAZOLE AND INTERMEDIATES THEREOF | Dynamit Nobel GmbH Explosivstoff- und Systemtechnik (DE) | 2011-05-25 | — | — | EP | claimed |
| WO-2010021409-A1 | METHODS FOR THE PRODUCTION OF 2-HALO-4-NITROIMIDAZOLE AND INTERMEDIATES THEREOF | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF - UND SYSTEMTECHNIK (DE) | 2010-02-25 | — | — | WO | claimed |
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | claimed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | claimed |
| US-20250361236-A9 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES INC (US) | 2025-11-27 | — | — | US | disclosed |
| US-20240400568-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2024-12-05 | — | — | US | disclosed |
| EP-4445902-A2 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | Carna Biosciences, Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| EP-4081305-B1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES INC (JP) | 2024-09-18 | — | — | EP | disclosed |
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| US-20240182476-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2024-06-06 | — | — | US | disclosed |
| US-7253199-B2 | Azole derivatives and pharmaceutical compositions containing them | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2007-08-07 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20030035917-A1 | Image making medium | HYMAN SYDNEY (US) | 2003-02-20 | — | — | US | disclosed |
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400568-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | DGKG, DGKB, DGKK | ATM 839/4885L3MBTL1 2745/4885RASGRP3 309/4885 |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | ATM 3644/4885L3MBTL1 1931/4885RASGRP3 2012/4885 |
| US-12054490-B2 | Diacylglycerol kinase modulating compounds | DGKG, DGKB, DGKK | ATM 839/4885L3MBTL1 2745/4885RASGRP3 309/4885 |
| US-20110178308-A1 | METHODS FOR THE PRODUCTION OF 2-HALO-4-NITROIMIDAZOLE AND INTERMEDIATES THEREOF | IL4I1, NUDT1, NISCH | ATM 3501/4885L3MBTL1 3231/4885RASGRP3 2701/4885 |
| US-20240182476-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | DGKG, DGKB, DGKK | ATM 839/4885L3MBTL1 2745/4885RASGRP3 309/4885 |
| US-20250361236-A9 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | DGKG, DGKB, DGKK | ATM 839/4885L3MBTL1 2745/4885RASGRP3 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.