Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634408 | 0.96 | ERCC1 (0.40) | ERCC1ERCC4MAPTHSD17B10HDAC1 | |
| SCHEMBL19634428 | 0.94 | ERCC1 (0.42) | ERCC1ERCC4HDAC1HDAC6ALDH1A1 | |
| SCHEMBL23471020 | 0.88 | KMT2A (0.43) | MAPTHSD17B10HDAC1HDAC6ALDH1A1 | |
| SCHEMBL19634735 | 0.88 | ERCC1 (0.37) | ERCC1ERCC4HSD17B10CA12CA1 | |
| SCHEMBL19634456 | 0.85 | HDAC6 (0.44) | MAPTHSD17B10HDAC1HDAC6CA1 | |
| SCHEMBL19634395 | 0.84 | MLYCD (0.46) | ERCC1ERCC4MAPTHSD17B10HDAC1 | |
| SCHEMBL23471017 | 0.83 | KMT2A (0.47) | MAPTHSD17B10HDAC1HDAC6ALDH1A1 | |
| SCHEMBL19634697 | 0.81 | LOXL2 (0.41) | MAPTHSD17B10HDAC1HDAC6CA2 | |
| SCHEMBL23471107 | 0.81 | KMT2A (0.49) | MAPTHDAC1HDAC6ALDH1A1RAB9A | |
| SCHEMBL21015966 | 0.81 | ERCC1 (0.41) | ERCC1ERCC4HSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |