Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634614 | 0.90 | HTT (0.40) | HTTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL19634525 | 0.89 | HTT (0.39) | HTTLMNAKCNN4KCNA5L3MBTL1 | |
| SCHEMBL8882499 | 0.81 | HTT (0.45) | HTTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL18121489 | 0.79 | CYP3A4 (0.33) | HTTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7523648 | 0.76 | GAA (0.45) | ALDH1A1KMT2AMEN1AOX1HSP90AA1 | |
| SCHEMBL808497 | 0.76 | MEN1 (0.41) | LMNAALDH1A1KMT2AMEN1AOX1 | |
| SCHEMBL18104688 | 0.75 | CYP3A4 (0.37) | HTTLMNAALDH1A1L3MBTL1GAA | |
| SCHEMBL11769205 | 0.74 | TDP1 (0.36) | HTTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL4821584 | 0.72 | MEN1 (0.42) | HTTALDH1A1KMT2AMEN1AOX1 | |
| SCHEMBL9802194 | 0.72 | AOX1 (0.47) | HTTLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |