Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11501984 | 0.79 | ALDH1A1 (0.35) | TDP1TSHRALOX15ALDH1A1HSP90AA1 | |
| SCHEMBL7523648 | 0.79 | GAA (0.45) | TDP1TSHRALOX15ALDH1A1HSP90AA1 | |
| SCHEMBL808497 | 0.79 | MEN1 (0.41) | TSHRALDH1A1HSP90AA1AOX1MEN1 | |
| SCHEMBL4821584 | 0.76 | MEN1 (0.42) | TSHRALDH1A1AOX1MEN1KMT2A | |
| SCHEMBL9802194 | 0.76 | AOX1 (0.47) | TSHRALOX15ALDH1A1HSP90AA1AOX1 | |
| SCHEMBL15187709 | 0.76 | ALDH1A1 (0.41) | TDP1ALOX15ALDH1A1ALOX12CA2 | |
| SCHEMBL18121489 | 0.74 | CYP3A4 (0.33) | TSHRALDH1A1HSP90AA1AOX1CFTR | |
| SCHEMBL19634601 | 0.74 | HTT (0.44) | TSHRALDH1A1HSP90AA1AOX1CFTR | |
| SCHEMBL8987951 | 0.74 | MEN1 (0.41) | MEN1KMT2ANPSR1L3MBTL1PKM | |
| SCHEMBL808442 | 0.73 | MEN1 (0.39) | TSHRALDH1A1HSP90AA1AOX1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064258-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | disclosed |