Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19634601 | 0.81 | HTT (0.44) | HTTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19634614 | 0.76 | HTT (0.40) | HTTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19634525 | 0.75 | HTT (0.39) | HTTLMNAL3MBTL1TSHRHIF1A | |
| SCHEMBL808442 | 0.72 | MEN1 (0.39) | LMNAALDH1A1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL7096547 | 0.70 | ALDH1A1 (0.36) | HTTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL377725 | 0.70 | HTT (0.40) | HTTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL27661786 | 0.70 | MEN1 (0.38) | LMNAALDH1A1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL10665143 | 0.70 | HSP90AA1 (0.35) | HTTLMNAALDH1A1KMT2AL3MBTL1 | |
| Bromide SCHEMBL28241411 | 0.70 | MEN1 (0.38) | LMNAALDH1A1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL8190077 | 0.70 | GAA (0.41) | HTTALDH1A1KMT2AHSP90AA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912668-B2 | GCN2 and perk kinase inhibitors and methods of use thereof | DECIPHERA PHARMACEUTICALS, LLC (US) | 2024-02-27 | — | — | US | disclosed |
| US-5644053-A | BETA-LACTAMASE INHIBITORS OR BACTERICIDE ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5637579-A | BETA-LACTAMASE INHIBITORS; BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1997-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912668-B2 | GCN2 and perk kinase inhibitors and methods of use thereof | EIF2AK4, GCN1, MAPKAPK2 | HTT 727/4885LMNA 770/4885ALDH1A1 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.