Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471208 | 0.88 | KMT2A (0.61) | KMT2AMEN1ALDH1A1LMNAPKM | |
| SCHEMBL19634465 | 0.88 | KMT2A (0.50) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL21015490 | 0.82 | KMT2A (0.60) | KMT2AMEN1ALDH1A1LMNAPKM | |
| SCHEMBL19634400 | 0.81 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1DRD2HRH3 | |
| SCHEMBL19634640 | 0.79 | LMNA (0.53) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL2377726 | 0.79 | HRH3 (0.64) | KMT2AMEN1LMNASMN1; SMN2HRH3 | |
| SCHEMBL8144500 | 0.78 | GRM5 (0.49) | KMT2AMEN1ALDH1A1LMNAPKM | |
| SCHEMBL19634410 | 0.76 | DRD2 (0.50) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL19634422 | 0.75 | MEN1 (0.49) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19634722 | 0.75 | NAMPT (0.55) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |