Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635547 | 0.83 | EPHX2 (0.33) | EPHX2PDE10A | |
| SCHEMBL19615303 | 0.83 | ALDH1A1 (0.34) | EPHX2PDE10A | |
| SCHEMBL6166773 | 0.65 | HTT (0.52) | EPHX2 | |
| SCHEMBL17594894 | 0.63 | MPO (0.43) | PDE10A | |
| SCHEMBL21889237 | 0.59 | AOC3 (0.39) | PDE10A | |
| SCHEMBL11629541 | 0.58 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL17045428 | 0.58 | NPC1 (0.40) | EPHX2PDE10A | |
| SCHEMBL19635867 | 0.57 | — | — | |
| SCHEMBL21301526 | 0.56 | PDE10A (0.52) | EPHX2PDE10A | |
| SCHEMBL6920216 | 0.56 | APAF1 (0.50) | CSNK2A2CSNK2BCSNK2A1CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458459-B1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AG (DE) | 2022-04-27 | — | — | EP | disclosed |
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |