Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458050 | 0.92 | ALDH1A1 (0.39) | ZDHHC20ZDHHC2ALDH1A1TSHRPSMB5 | |
| SCHEMBL8040319 | 0.86 | ALDH1A1 (0.45) | ZDHHC20ZDHHC2ALDH1A1TSHRPSMB5 | |
| SCHEMBL14880 | 0.85 | — | — | |
| SCHEMBL16098956 | 0.84 | ZDHHC20 (0.39) | ZDHHC20ZDHHC2ALDH1A1TSHRPSMB5 | |
| Ammonia Solution, Strong SCHEMBL28481040 | 0.83 | ZDHHC20 (0.43) | ZDHHC20ZDHHC2ALDH1A1TSHRPSMB5 | |
| SCHEMBL18705058 | 0.83 | ZDHHC20 (0.45) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL18705059 | 0.83 | ZDHHC20 (0.45) | ZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL2004205 | 0.81 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2ALDH1A1TSHRPSMB5 | |
| SCHEMBL423989 | 0.79 | — | — | |
| SCHEMBL15617163 | 0.79 | ALDH1A1 (0.46) | ZDHHC20ZDHHC2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11000454-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20190117523-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2017198840-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11000454-B2 | Dental composition | PPIP5K2, INPP5D, DCPS | ZDHHC20 1646/4885ZDHHC2 2407/4885ALDH1A1 1990/4885 |
| US-20190117523-A1 | DENTAL COMPOSITION | PPIP5K2, INPP5D, DCPS | ZDHHC20 1646/4885ZDHHC2 2407/4885ALDH1A1 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.