Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19636115 | 0.92 | ZDHHC20 (0.40) | ALDH1A1ZDHHC20ZDHHC2TSHRPSMB5 | |
| SCHEMBL8040319 | 0.92 | ALDH1A1 (0.45) | ALDH1A1ZDHHC20ZDHHC2SLC6A4SLC6A2 | |
| SCHEMBL15617163 | 0.90 | ALDH1A1 (0.46) | ALDH1A1ZDHHC20ZDHHC2MAPTDPP4 | |
| SCHEMBL18106220 | 0.90 | ALDH1A1 (0.46) | ALDH1A1ZDHHC20ZDHHC2MAPTDPP4 | |
| SCHEMBL21652434 | 0.85 | ALDH1A1 (0.46) | ALDH1A1ZDHHC20ZDHHC2MAPTTSHR | |
| SCHEMBL18734536 | 0.85 | ZDHHC20 (0.41) | ALDH1A1ZDHHC20ZDHHC2MAPTTSHR | |
| SCHEMBL19493415 | 0.85 | ALDH1A1 (0.44) | ALDH1A1ZDHHC20ZDHHC2DPP4SMN1; SMN2 | |
| SCHEMBL19620229 | 0.84 | ALDH1A1 (0.42) | ALDH1A1ZDHHC20ZDHHC2MAPTSMN1; SMN2 | |
| SCHEMBL49389 | 0.83 | ALDH1A1 (0.52) | ALDH1A1ZDHHC20ZDHHC2MAPTTSHR | |
| SCHEMBL20274381 | 0.82 | ALDH1A1 (0.41) | ALDH1A1ZDHHC20ZDHHC2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11141357-B2 | Dental adhesive | DENTSPLY SIRONA INC. (US) | 2021-10-12 | — | — | US | disclosed |
| US-20210137795-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2021-05-13 | — | — | US | disclosed |
| WO-2017017155-A1 | DENTAL ADHESIVE | DENTSPLY DETREY GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11141357-B2 | Dental adhesive | CDH1, ITGA5, ICAM1 | ALDH1A1 404/4885ZDHHC20 2687/4885ZDHHC2 3453/4885 |
| US-20210137795-A1 | DENTAL ADHESIVE | CDH1, ITGA5, ICAM1 | ALDH1A1 404/4885ZDHHC20 2687/4885ZDHHC2 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.