Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19637172 | 0.68 | HTT (0.32) | HTT | |
| SCHEMBL19637369 | 0.68 | HTT (0.35) | HTT | |
| SCHEMBL19637255 | 0.66 | HTT (0.34) | HTT | |
| SCHEMBL15904221 | 0.65 | NOS3 (0.31) | — | |
| SCHEMBL19637079 | 0.64 | HTT (0.32) | HTT | |
| SCHEMBL19592703 | 0.62 | NUDT1 (0.39) | — | |
| SCHEMBL21895750 | 0.62 | SMN1; SMN2 (0.41) | HTT | |
| SCHEMBL19491732 | 0.62 | TTK (0.38) | — | |
| SCHEMBL19637432 | 0.61 | KDM4E (0.36) | — | |
| SCHEMBL12483331 | 0.60 | KDM4E (0.56) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3458445-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2020101736-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-05-22 | — | — | WO | disclosed |
| WO-2017201161-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-11-23 | — | — | WO | disclosed |