SCHEMBL19638027

SCHEMBL19638027

O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1Cl

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 12/20 0.77
P2RX7 Q99572 6/20 0.77
P2RX4 Q99571 5/20 0.77
TMPRSS4 Q9NRS4 3/20 0.77
RXFP1 Q9HBX9 1/20 0.70
TLR7 Q9NYK1 1/20 0.64
MAPT P10636 2/20 0.62
THRB P10828 1/20 0.62
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
IKBKB O14920 1/20 0.62
CHUK O15111 1/20 0.62
KDR P35968 1/20 0.62
FLT3 P36888 1/20 0.62
MYLK Q15746 1/20 0.62
MAP4K5 Q9Y4K4 1/20 0.62
RORC P51449 1/20 0.62
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.60
HTT P42858 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29891420 1.00 P2RX1 (0.77) P2RX1P2RX7P2RX4TMPRSS4RXFP1
SCHEMBL3455896 0.88 RXFP1 (0.88) P2RX1P2RX7P2RX4TMPRSS4RXFP1
SCHEMBL14885879 0.87 P2RX1 (1.00) P2RX1P2RX7P2RX4TMPRSS4RXFP1
SCHEMBL5369677 0.86 RORC (0.76) P2RX1P2RX7P2RX4TMPRSS4RXFP1
SCHEMBL15171235 0.84 TLR8 (0.76) P2RX1P2RX7P2RX4TMPRSS4RXFP1
SCHEMBL127962 0.83 P2RX1 (1.00) P2RX1P2RX7P2RX4TMPRSS4MEN1
SCHEMBL10797383 0.83 P2RX1 (0.73) P2RX1P2RX7P2RX4TMPRSS4RXFP1
SCHEMBL15528915 0.83 RXFP1 (1.00) RXFP1MAPTMEN1KMT2AALDH1A1
SCHEMBL5666099 0.82 P2RX1 (1.00) P2RX1P2RX7P2RX4TMPRSS4RXFP1
SCHEMBL26634737 0.82 P2RX1 (0.77) P2RX1P2RX7P2RX4TMPRSS4RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623942-B2 Method for extracting salts and temperature- regenerated extracting composition ADIONICS (FR) 2026-05-12 US disclosed
CN-113292128-B Apparatus and method for desalting water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2024-07-05 CN disclosed
US-20230382775-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2023-11-30 US disclosed
US-11772997-B2 Method for extracting salts and temperature-regenerated extracting composition ADIONICS (FR) 2023-10-03 US disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
CN-113200938-B Benzisothiazole hypoxia inducible factor 2 agonist compound or pharmaceutically acceptable salt thereof, preparation method and application 中国药科大学 2022-08-26 CN disclosed
CN-109641160-B Method for extracting salt and temperature-regenerated extraction composition 艾迪奥尼克斯公司 2022-02-25 CN disclosed
EP-3247677-B1 LIQUID ORGANIC COMPOSITION FOR ION EXTRACTION IN LIQUID PHASE ADIONICS (FR) 2021-12-08 EP disclosed
US-20210355076-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2021-11-18 US disclosed
CN-113292128-A Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2021-08-24 CN disclosed
CN-113200938-A Benzisothiazole hypoxia inducible factor 2 agonist compound or pharmaceutically acceptable salt thereof, preparation method and application 中国药科大学 2021-08-03 CN disclosed
US-11066356-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2021-07-20 US disclosed
US-20210214254-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2021-07-15 US disclosed
CN-107207288-B Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2021-07-06 CN disclosed
EP-3808425-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2021-04-21 EP disclosed
EP-3487597-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION Adionics (FR) 2019-05-29 EP disclosed
CN-109641160-A Extract the method for salt and the extracts composition of temperature regeneration 艾迪奥尼克斯公司 2019-04-16 CN disclosed
US-20180009738-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2018-01-11 US disclosed
EP-3247677-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2017-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 P2RX1 2832/4885P2RX7 2431/4885P2RX4 2933/4885
US-20210355076-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID AQP3, AQP1, AQP4 P2RX1 2832/4885P2RX7 2431/4885P2RX4 2933/4885
US-12623942-B2 Method for extracting salts and temperature- regenerated extracting composition POLQ, NONO, AQP3 P2RX1 2777/4885P2RX7 2083/4885P2RX4 2605/4885
US-20180009738-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID AQP3, AQP1, AQP4 P2RX1 2832/4885P2RX7 2431/4885P2RX4 2933/4885
US-11066356-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 P2RX1 2832/4885P2RX7 2431/4885P2RX4 2933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.