SCHEMBL19638032

SCHEMBL19638032

CCCCCCCC(=O)Nc1cc(C(F)(F)F)ccc1Cl

nearest known ligand 0.79

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.79
HDAC8 Q9BY41 1/20 0.79
ALDH1A1 P00352 7/20 0.71
MAPT P10636 2/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
CYP2C19 P33261 4/20 0.64
CYP3A4 P08684 3/20 0.64
CYP2D6 P10635 3/20 0.64
CYP1A2 P05177 3/20 0.57
RAB9A P51151 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
TP53 P04637 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30977686 1.00 HDAC1 (0.79) HDAC1HDAC8ALDH1A1MAPTSMN1; SMN2
SCHEMBL5150800 0.84 HDAC1 (0.74) HDAC1HDAC8ALDH1A1MAPTSMN1; SMN2
SCHEMBL19638020 0.84 ALDH1A1 (0.65) HDAC1HDAC8ALDH1A1MAPTSMN1; SMN2
SCHEMBL11336837 0.82 ALDH1A1 (0.61) HDAC1HDAC8ALDH1A1MAPTSMN1; SMN2
SCHEMBL7824102 0.81 ALDH1A1 (0.70) HDAC1HDAC8ALDH1A1MAPTSMN1; SMN2
SCHEMBL16914805 0.81 NPSR1 (0.65) HDAC1HDAC8ALDH1A1MAPTSMN1; SMN2
SCHEMBL2346035 0.80 ALDH1A1 (0.67) HDAC1HDAC8ALDH1A1MEN1KMT2A
SCHEMBL31492222 0.79 ALDH1A1 (0.67) HDAC1HDAC8ALDH1A1SMN1; SMN2MEN1
SCHEMBL4006377 0.79 ALDH1A1 (0.67) HDAC1HDAC8ALDH1A1SMN1; SMN2MEN1
SCHEMBL8288257 0.78 ALDH1A1 (0.65) HDAC1HDAC8ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623942-B2 Method for extracting salts and temperature- regenerated extracting composition ADIONICS (FR) 2026-05-12 US disclosed
CN-113292128-B Apparatus and method for desalting water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2024-07-05 CN disclosed
US-20230382775-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2023-11-30 US disclosed
US-11772997-B2 Method for extracting salts and temperature-regenerated extracting composition ADIONICS (FR) 2023-10-03 US disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
CN-109641160-B Method for extracting salt and temperature-regenerated extraction composition 艾迪奥尼克斯公司 2022-02-25 CN disclosed
US-20210355076-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2021-11-18 US disclosed
CN-113292128-A Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2021-08-24 CN disclosed
US-11066356-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2021-07-20 US disclosed
US-20210214254-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2021-07-15 US disclosed
CN-107207288-B Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2021-07-06 CN disclosed
CN-109280362-B Thermoplastic polyurethane open master batch and application thereof 广州增城市大发塑胶颜料有限公司 2021-05-25 CN disclosed
EP-3808425-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2021-04-21 EP disclosed
EP-3487597-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION Adionics (FR) 2019-05-29 EP disclosed
CN-109641160-A Extract the method for salt and the extracts composition of temperature regeneration 艾迪奥尼克斯公司 2019-04-16 CN disclosed
US-20180009738-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2018-01-11 US disclosed
EP-3247677-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2017-11-29 EP disclosed
CN-107207288-A Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2017-09-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 HDAC1 2778/4885HDAC8 3736/4885ALDH1A1 3499/4885
US-20210355076-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID AQP3, AQP1, AQP4 HDAC1 2778/4885HDAC8 3736/4885ALDH1A1 3499/4885
US-12623942-B2 Method for extracting salts and temperature- regenerated extracting composition POLQ, NONO, AQP3 HDAC1 1822/4885HDAC8 3518/4885ALDH1A1 3793/4885
US-20180009738-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID AQP3, AQP1, AQP4 HDAC1 2778/4885HDAC8 3736/4885ALDH1A1 3499/4885
US-11066356-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 HDAC1 2778/4885HDAC8 3736/4885ALDH1A1 3499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.