SCHEMBL19638020

SCHEMBL19638020

CCC(=O)Nc1cc(C(F)(F)F)ccc1Cl

nearest known ligand 0.72

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.65
CYP2C19 P33261 3/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
CYP1A2 P05177 2/20 0.65
CYP3A4 P08684 2/20 0.65
HDAC1 Q13547 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
CYP2D6 P10635 3/20 0.63
L3MBTL1 Q9Y468 2/20 0.62
HTT P42858 2/20 0.60
MAPT P10636 2/20 0.60
MAPK1 P28482 1/20 0.60
KDM4E B2RXH2 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
POLB P06746 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2346035 0.87 ALDH1A1 (0.67) ALDH1A1CYP2C19MEN1KMT2ACYP1A2
SCHEMBL31492222 0.86 ALDH1A1 (0.67) ALDH1A1CYP2C19MEN1KMT2ACYP1A2
SCHEMBL4006377 0.86 ALDH1A1 (0.67) ALDH1A1CYP2C19MEN1KMT2ACYP1A2
SCHEMBL8288257 0.85 ALDH1A1 (0.65) ALDH1A1CYP2C19MEN1KMT2ACYP1A2
SCHEMBL30977686 0.84 HDAC1 (0.79) ALDH1A1CYP2C19MEN1KMT2ACYP1A2
SCHEMBL19638032 0.84 HDAC1 (0.79) ALDH1A1CYP2C19MEN1KMT2ACYP1A2
SCHEMBL13170074 0.83 MEN1 (0.60) ALDH1A1CYP2C19MEN1KMT2ACYP1A2
SCHEMBL7824102 0.82 ALDH1A1 (0.70) ALDH1A1CYP2C19MEN1KMT2ACYP1A2
SCHEMBL29776952 0.82 CHRNA7 (0.76) ALDH1A1CYP2C19MEN1KMT2ACYP1A2
SCHEMBL20472469 0.82 CHRNA7 (0.76) ALDH1A1CYP2C19MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623942-B2 Method for extracting salts and temperature- regenerated extracting composition ADIONICS (FR) 2026-05-12 US disclosed
CN-113292128-B Apparatus and method for desalting water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2024-07-05 CN disclosed
US-20230382775-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2023-11-30 US disclosed
US-11772997-B2 Method for extracting salts and temperature-regenerated extracting composition ADIONICS (FR) 2023-10-03 US disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
CN-109641160-B Method for extracting salt and temperature-regenerated extraction composition 艾迪奥尼克斯公司 2022-02-25 CN disclosed
US-20210355076-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2021-11-18 US disclosed
CN-113292128-A Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2021-08-24 CN disclosed
US-11066356-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2021-07-20 US disclosed
US-20210214254-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION ADIONICS (FR) 2021-07-15 US disclosed
CN-107207288-B Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2021-07-06 CN disclosed
EP-3808425-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2021-04-21 EP disclosed
EP-3487597-A1 METHOD FOR EXTRACTING SALTS AND TEMPERATURE-REGENERATED EXTRACTING COMPOSITION Adionics (FR) 2019-05-29 EP disclosed
CN-109641160-A Extract the method for salt and the extracts composition of temperature regeneration 艾迪奥尼克斯公司 2019-04-16 CN disclosed
US-20180009738-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2018-01-11 US disclosed
EP-3247677-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID ADIONICS (FR) 2017-11-29 EP disclosed
CN-107207288-A Apparatus and method for desalination of water by thermal deionization and liquid phase ion extraction 艾迪奥尼克斯公司 2017-09-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 ALDH1A1 3499/4885CYP2C19 3157/4885MEN1 4431/4885
US-20210355076-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID AQP3, AQP1, AQP4 ALDH1A1 3499/4885CYP2C19 3157/4885MEN1 4431/4885
US-12623942-B2 Method for extracting salts and temperature- regenerated extracting composition POLQ, NONO, AQP3 ALDH1A1 3793/4885CYP2C19 3126/4885MEN1 4052/4885
US-20180009738-A1 DEVICE AND METHOD FOR THE DESALINATION OF WATER BY MEANS OF THERMAL DEIONISATION AND LIQUID-PHASE ION EXTRACTION LIQUID AQP3, AQP1, AQP4 ALDH1A1 3499/4885CYP2C19 3157/4885MEN1 4431/4885
US-11066356-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 ALDH1A1 3499/4885CYP2C19 3157/4885MEN1 4431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.