Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964083 | 0.81 | ACHE (0.66) | ACHESIRT2SIRT1KMT2AMEN1 | |
| SCHEMBL2578048 | 0.80 | SIRT2 (0.41) | ACHESIRT2SIRT1CYP1A2CYP2D6 | |
| SCHEMBL2581182 | 0.79 | ACHE (0.48) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL2577267 | 0.76 | ACHE (0.49) | ACHESIRT2SIRT1KMT2AMEN1 | |
| SCHEMBL4923632 | 0.73 | ACHE (0.48) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL16589753 | 0.73 | ACHE (0.54) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL4919773 | 0.72 | SIRT2 (0.52) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL4923540 | 0.72 | ACHE (0.52) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL515217 | 0.71 | ACHE (0.51) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL1967075 | 0.70 | ACHE (0.60) | ACHECA12CA9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048825-B2 | Haloalkylsulfonanilide derivatives or salt thereof, herbicide comprising the derivatives as active ingredient, and use of the herbicide | NIHON NOHYAKU CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20100016164-A1 | HALOALKYLSULFONANILIDE DERIVATIVES OR SALT THEREOF, HERBICIDE COMPRISING THE DERIVATIVES AS ACTIVE INGREDIENT, AND USE OF THE HERBICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-2085392-A1 | HALOALKYLSULFONANILIDE DERIVATIVE OR SALT THEREOF, HERBICIDE COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT, AND USE OF THE HERBICIDE | Nihon Nohyaku CO., LTD. (JP) | 2009-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016164-A1 | HALOALKYLSULFONANILIDE DERIVATIVES OR SALT THEREOF, HERBICIDE COMPRISING THE DERIVATIVES AS ACTIVE INGREDIENT, AND USE OF THE HERBICIDE | HDHD5, CBR3, DHRS9 | ACHE 190/4885SIRT2 2413/4885SIRT1 2520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.