Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 8/20 | 1.00 |
| ▸ | MAOB | P27338 | 12/20 | 0.86 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.75 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | BCHE | P06276 | 1/20 | 0.75 |
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.75 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.75 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.72 |
| ▸ | MAOA | P21397 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.71 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196425 | 1.00 | CYP1B1 (1.00) | CYP1B1MAOBMAPTTNFRSF1APLIN1 | |
| SCHEMBL10415521 | 1.00 | CYP1B1 (1.00) | CYP1B1MAOBMAPTTNFRSF1APLIN1 | |
| 4-Chloro Chalcone SCHEMBL198518 | 0.93 | MAOB (1.00) | CYP1B1MAOBMAPTTNFRSF1APLIN1 | |
| 4-Chloro Chalcone SCHEMBL197311 | 0.93 | MAOB (1.00) | CYP1B1MAOBMAPTTNFRSF1APLIN1 | |
| 4-Chloro Chalcone SCHEMBL197310 | 0.93 | MAOB (1.00) | CYP1B1MAOBMAPTTNFRSF1APLIN1 | |
| 4',4-Dichlorochalcone SCHEMBL659210 | 0.90 | MAOB (0.86) | CYP1B1MAOBMAPTTNFRSF1ACXCL12 | |
| 4',4-Dichlorochalcone SCHEMBL659211 | 0.90 | MAOB (0.86) | CYP1B1MAOBMAPTTNFRSF1ACXCL12 | |
| SCHEMBL2648476 | 0.90 | MAOB (0.81) | CYP1B1MAOBMAPTTNFRSF1APLIN1 | |
| SCHEMBL2664997 | 0.90 | MAOB (0.81) | CYP1B1MAOBMAPTTNFRSF1APLIN1 | |
| SCHEMBL657311 | 0.90 | MAOB (0.81) | CYP1B1MAOBMAPTTNFRSF1APLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192224-A | Alpha, beta-unsaturated ketone cyano silanization method and application | 哈尔滨理工大学 | 2024-12-27 | — | — | CN | claimed |
| CN-117384199-A | Preparation of novel organic aluminum hydrogen compound and preparation method of unsaturated alcohol compound catalyzed by novel organic aluminum hydrogen compound | 北京理工大学 | 2024-01-12 | — | — | CN | claimed |
| CN-111233645-A | Method for preparing tri-substituted cyclopentene by MBH/Wittig domino reaction of vinylon insertion | 浙江大学 | 2020-06-05 | — | — | CN | claimed |
| US-9334253-B2 | Direct trifluoromethylations using trifluoromethane | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2016-05-10 | — | — | US | claimed |
| US-20140066640-A1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-06 | — | — | US | claimed |
| WO-2012148772-A1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2012-11-01 | — | — | WO | claimed |
| EP-4567018-A1 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-06-11 | — | — | EP | disclosed |
| US-20250051299-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | DAIKIN INDUSTRIES, LTD. (JP) | 2025-02-13 | — | — | US | disclosed |
| CN-119192224-A | Alpha, beta-unsaturated ketone cyano silanization method and application | 哈尔滨理工大学 | 2024-12-27 | — | — | CN | disclosed |
| US-12162854-B2 | Production method for fluoromethyl derivative | DAIKIN INDUSTRIES, LTD. (JP) | 2024-12-10 | — | — | US | disclosed |
| WO-2024029525-A1 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND | ダイキン工業株式会社 | 2024-02-08 | — | — | WO | disclosed |
| CN-117384199-A | Preparation of novel organic aluminum hydrogen compound and preparation method of unsaturated alcohol compound catalyzed by novel organic aluminum hydrogen compound | 北京理工大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-115368268-B | Method for efficiently preparing azo compound and application thereof | 大连理工大学 | 2023-11-17 | — | — | CN | disclosed |
| US-20070155617-A1 | FUNCTIONAL GROUP-SELECTIVE HYDROGENATION CATALYST AND FUNCTIONAL GROUP-SELECTIVE HYDROGENATION METHOD | N. E. CHEMCAT CORPORATION (JP) | 2007-07-05 | — | — | US | disclosed |
| CN-1438890-A | Adenosine receptor modulators | HOFFMANNLA ROCHE AG F (CH) | 2003-08-27 | — | — | CN | disclosed |
| US-6586441-B2 | 2-Amino-6-benzylsulfanyl-4-thiophen-2-yl-pyridine-3,5-dicarbo -nitrile as an examplary preferred compound; Alzheimer's and Parkinson's diseases; neuroprotectors; schizophrenia, analgesics; anxiolytic agents; respiratory disorders | HOFFMAN-LA ROCHE INC. | 2003-07-01 | — | — | US | disclosed |
| EP-1261327-A2 | ADENOSINE RECEPTOR MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2002-12-04 | — | — | EP | disclosed |
| US-20010027196-A1 | Adenosine receptor ligands and their use in the treatment of disease | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-04 | — | — | US | disclosed |
| WO-2001062233-A2 | ADENOSINE RECEPTOR MODULATORS | F. HOFFMANN LA ROCHE AG (CH) | 2001-08-30 | — | — | WO | disclosed |
| EP-0236913-A2 | Aryl-azolylmethyl-benzocyclo-alkene derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010027196-A1 | Adenosine receptor ligands and their use in the treatment of disease | ADORA2A, ADORA2B, ADORA1 | CYP1B1 867/4885MAOB 157/4885MAPT 1878/4885 |
| US-20140066640-A1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | TST, FLI1, CYP2F1 | CYP1B1 1586/4885MAOB 2391/4885MAPT 3128/4885 |
| US-12162854-B2 | Production method for fluoromethyl derivative | AFF1, AFF2, ROS1 | CYP1B1 23/4885MAOB 20/4885MAPT 3085/4885 |
| US-20250051299-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | AFF1, AFF2, ROS1 | CYP1B1 23/4885MAOB 20/4885MAPT 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.