Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19644618 | 0.84 | AR (0.37) | GRM5NPC1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL19645005 | 0.83 | LMNA (0.41) | GRM5SMN1; SMN2LMNAL3MBTL1KDM4E | |
| SCHEMBL19644622 | 0.80 | LMNA (0.38) | GRM5SMN1; SMN2LMNAL3MBTL1KDM4E | |
| SCHEMBL19630405 | 0.79 | MAOA (0.40) | GRM5NPC1SMN1; SMN2MAOBLMNA | |
| SCHEMBL19644942 | 0.78 | ALDH1A1 (0.38) | NTSR1TP53NPC1SMN1; SMN2LMNA | |
| SCHEMBL19645002 | 0.77 | PDE10A (0.38) | NTSR1TP53NPC1SMN1; SMN2MAOB | |
| SCHEMBL19644943 | 0.76 | TSPO (0.38) | GRM5NPC1SMN1; SMN2MAOBLMNA | |
| SCHEMBL13010236 | 0.74 | L3MBTL1 (0.55) | LMNAL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL12455311 | 0.74 | L3MBTL1 (0.55) | LMNAL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL30516185 | 0.74 | L3MBTL1 (0.55) | LMNAL3MBTL1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9831444-B1 | Phenanthroline-based compound for organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2017-11-28 | — | — | US | disclosed |