SCHEMBL19652014

SCHEMBL19652014

O=C1C(=Cc2ccc(N(c3ccc(F)cc3)c3cccc4ccccc34)o2)C(=O)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.41
POLB P06746 5/20 0.41
L3MBTL1 Q9Y468 5/20 0.41
PKM P14618 2/20 0.41
CTDSP1 Q9GZU7 2/20 0.41
HPGD P15428 2/20 0.41
RECQL P46063 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPK1 P28482 1/20 0.41
MCL1 Q07820 1/20 0.41
MEN1 O00255 6/20 0.35
KMT2A Q03164 6/20 0.35
ALDH1A1 P00352 2/20 0.35
HTT P42858 2/20 0.35
RAB9A P51151 2/20 0.34
CES1 P23141 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
USP1 O94782 1/20 0.33
USP19 O94966 1/20 0.33
UCHL3 P15374 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19652008 0.91 MAPT (0.45) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652016 0.86 MAPT (0.51) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652022 0.84 MAPT (0.49) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652013 0.81 SIGMAR1 (0.34) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652017 0.78 MAPT (0.38) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652005 0.77 KMT2A (0.48) MAPTPOLBL3MBTL1PKMHPGD
SCHEMBL19652011 0.76 MAPT (0.56) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL22108460 0.75 MEN1 (0.40) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652012 0.74 MAPT (0.51) MAPTPOLBL3MBTL1PKMCTDSP1
SCHEMBL19652010 0.74 MAPT (0.46) MAPTPOLBL3MBTL1PKMCTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CYP1A1 MAPT 2370/4885POLB 1592/4885L3MBTL1 3762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.