SCHEMBL19652017

SCHEMBL19652017

O=C1C(=Cc2ccc(N(c3ccc(F)cc3)c3ccc(F)cc3)o2)C(=O)c2c1c1ccccc1c1ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.38
KMT2A Q03164 7/20 0.38
MEN1 O00255 6/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PKM P14618 4/20 0.36
L3MBTL1 Q9Y468 4/20 0.36
HPGD P15428 3/20 0.36
POLB P06746 2/20 0.36
RECQL P46063 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MAPK1 P28482 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
MCL1 Q07820 1/20 0.36
NPC1 O15118 1/20 0.34
IDE P14735 1/20 0.34
CES1 P23141 1/20 0.31
ALDH1A1 P00352 3/20 0.31
GPR55 Q9Y2T6 2/20 0.31
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19652016 0.86 MAPT (0.51) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL19652022 0.84 MAPT (0.49) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL19652013 0.79 SIGMAR1 (0.34) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL19652014 0.78 MAPT (0.41) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL22108463 0.78 MAPT (0.42) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL19652026 0.75 DNMT1 (0.40) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL19652011 0.74 MAPT (0.56) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL19652012 0.73 MAPT (0.51) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL22108616 0.70 MAPT (0.38) MAPTKMT2AMEN1RAB9ASMN1; SMN2
SCHEMBL19652018 0.70 MAPT (0.44) MAPTKMT2AMEN1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CYP1A1 MAPT 2370/4885KMT2A 1370/4885MEN1 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.