SCHEMBL19652013

SCHEMBL19652013

O=C1C(=Cc2ccc(N(c3ccccc3)c3cccc4ccccc34)o2)C(=O)c2c1c1ccccc1c1ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.34
MAPT P10636 5/20 0.33
L3MBTL1 Q9Y468 4/20 0.33
KMT2A Q03164 4/20 0.33
POLB P06746 3/20 0.33
MEN1 O00255 3/20 0.33
PKM P14618 2/20 0.33
HPGD P15428 2/20 0.33
RECQL P46063 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
RAB9A P51151 2/20 0.33
MAPK1 P28482 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
MCL1 Q07820 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.33
PLA2G1B P04054 1/20 0.33
DNMT1 P26358 1/20 0.33
PPARG P37231 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19652008 0.90 MAPT (0.45) SIGMAR1MAPTL3MBTL1KMT2APOLB
SCHEMBL22108460 0.82 MEN1 (0.40) SIGMAR1MAPTL3MBTL1KMT2APOLB
SCHEMBL19652014 0.81 MAPT (0.41) MAPTL3MBTL1KMT2APOLBMEN1
SCHEMBL19652005 0.81 KMT2A (0.48) SIGMAR1MAPTL3MBTL1KMT2APOLB
SCHEMBL19652026 0.81 DNMT1 (0.40) MAPTL3MBTL1KMT2APOLBMEN1
SCHEMBL19652017 0.79 MAPT (0.38) MAPTL3MBTL1KMT2APOLBMEN1
SCHEMBL8204842 0.77 SIGMAR1 (0.44) SIGMAR1L3MBTL1KMT2ATDP1KDM4E
SCHEMBL18683393 0.75 ALDH1A1 (0.33) SIGMAR1MAPTKMT2AHPGDRECQL
SCHEMBL19652024 0.74 ESR2 (0.43) MAPTL3MBTL1KMT2APOLBMEN1
SCHEMBL19652018 0.74 MAPT (0.44) MAPTL3MBTL1KMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CYP1A1 SIGMAR1 3029/4885MAPT 2370/4885L3MBTL1 3762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.