SCHEMBL19655252

SCHEMBL19655252

c1ccc(-c2nc3c4ccccc4c4ccccc4c3nc2-c2cccc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc7c6oc6ccccc67)c5c43)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.33
PTGER1 P34995 1/20 0.33
CSF1R P07333 1/20 0.33
PDGFRB P09619 1/20 0.33
KIT P10721 1/20 0.33
FLT3 P36888 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PRKDC P78527 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GAA P10253 1/20 0.30
ALOX5 P09917 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655199 0.91 MEN1 (0.35) MEN1KMT2AMAPTPTGER1CSF1R
SCHEMBL19655235 0.87 MAPT (0.35) MEN1KMT2AMAPTPTGER1CSF1R
SCHEMBL23203963 0.86 KDM4E (0.37) MEN1KMT2APRKDCKDM4EATM
SCHEMBL19655248 0.86 L3MBTL1 (0.42) MEN1KMT2AMAPTKDM4EATM
SCHEMBL17809143 0.85 MAPT (0.36) MEN1KMT2AMAPTKDM4EATM
SCHEMBL26413259 0.85 KDM4E (0.36) MEN1KMT2APRKDCKDM4EATM
SCHEMBL19655246 0.84 L3MBTL1 (0.41) MEN1KMT2AMAPTKDM4EATM
SCHEMBL17809148 0.84 MAPT (0.35) MEN1KMT2AMAPTPRKDCKDM4E
SCHEMBL17809140 0.84 KDM4E (0.32) MEN1KMT2AMAPTCSF1RPDGFRB
SCHEMBL17809142 0.84 MAPT (0.34) MEN1KMT2AMAPTKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-11-17 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346022-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDXK, MT-ND4L, PNPO MEN1 2827/4885KMT2A 3170/4885MAPT 2438/4885
US-10840458-B2 Organic electroluminescent materials and devices PDXK, MT-ND4L, PNPO MEN1 2827/4885KMT2A 3170/4885MAPT 2438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.