SCHEMBL19655459

SCHEMBL19655459

Cc1sc(C)c(SCSc2ccccc2)c1SCSc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
MAPK1 P28482 1/20 0.43
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
POLB P06746 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
FFAR1 O14842 1/20 0.36
MAPT P10636 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
HTT P42858 1/20 0.35
PLA2G1B P04054 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ATG4B Q9Y4P1 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19655451 0.84 ALDH1A1 (0.60) ALDH1A1MAPK1MAOAMAOBPOLB
SCHEMBL19655461 0.82 ALDH1A1 (0.34) ALDH1A1MAPK1MAOAMAOBPOLB
SCHEMBL19655456 0.81 DHFR (0.36) ALDH1A1MAOAMAOBPOLBL3MBTL1
SCHEMBL777671 0.78 ALDH1A1 (0.67) ALDH1A1MAPK1MAOAMAOBFFAR1
SCHEMBL12110783 0.75 ALDH1A1 (0.63) ALDH1A1MAPK1MAOAMAOBFFAR1
SCHEMBL11661294 0.69 ALDH1A1 (0.55) ALDH1A1MAPK1MAOAMAOBPOLB
SCHEMBL12110681 0.68 ALDH1A1 (0.60) ALDH1A1MAPK1MAOAMAOBFFAR1
SCHEMBL19655448 0.66 NPC1 (0.40) ALDH1A1MAPK1MAPTL3MBTL1HTT
SCHEMBL24089845 0.64 ALDH1A1 (0.55) ALDH1A1MAPK1MAOAMAOBFFAR1
SCHEMBL30255528 0.64 MAOA (0.52) ALDH1A1MAPK1MAOAMAOBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9991518-B2 Polythiophene derivative, method for producing same, positive electrode active material for secondary batteries, and secondary battery RICOH COMPANY, LTD. (JP) 2018-06-05 US disclosed
US-20170346095-A1 POLYTHIOPHENE DERIVATIVE, METHOD FOR PRODUCING SAME, POSITIVE ELECTRODE ACTIVE MATERIAL FOR SECONDARY BATTERIES, AND SECONDARY BATTERY RICOH COMPANY, LTD. (JP) 2017-11-30 US disclosed